ED affects millions of men worldwide. It is a sexual dysfunction that can be serious and even life-threatening. Tadalafil is the newest PDE5 inhibitor to treat ED. It works by increasing blood flow to the penis.
Efficacy
Tadalafil medications for ED is particularly need for males as it can improve their erections and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate). The symptoms include difficulty urinating, painful urination, and urinary frequency and urgency.
Tadalafil is a phosphodiesterase (PDE) inhibitor and works by increasing blood flow to the penis during sexual stimulation. It is also use to treat pulmonary arterial hypertension (PAH; high pressure in the vessels carrying blood to the lungs), which can cause shortness of breath, dizziness, and tiredness.
Tadalafil is available in a 5 and 10 mg tablet. It has a longer half-life than the other PDE5 inhibitors and is therefore able to achieve a steady state of serum concentration with low dose, once daily dosing. Moreover, once-daily dosing can be more convenient than on-demand dosing, which requires frequent refilling. However, dosing with Vidalista pill may increase the risk of orthostatic hypotension. This is because it can lower your blood pressure when you stand up.
Side effects
Tadalafil medications for ED is particularly need for males as they can help treat the symptoms of benign prostatic hyperplasia (BPH), erectile dysfunction (ED), and pulmonary arterial hypertension (PAH). BPH is an enlarged prostate gland that pinches or squeezes your urethra, the tube that carries urine from your kidneys out of your body. ED is when your penis doesn’t fill up with enough blood to harden and expand when you are sexually arouse.
The Vidalista 5 pill pill works by increasing the flow of blood to your penis. It also relaxes the muscle in your prostate and bladder to improve the symptoms of BPH.
It also increases the flow of blood to your lungs to help you exercise better. It also lowers your blood pressure by relaxing the walls of your arteries.
If you take tadalafil with certain alpha blockers that are sometimes use to treat prostate problems or high blood pressure, your blood pressure could suddenly drop to dangerously low levels. This can cause dizziness, a headache, and fainting. It may also make your heart beat faster and increase the chance of a serious heart problem called orthostatic hypotension.
Tolerability
Erectile dysfunction (ED) is a common symptom of sexual dissatisfaction in men. It can affect quality of life, relationships and family stability. Medications such as sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) can be use to treat ED.
Tadalafil is metabolize to a catechol metabolite that undergoes extensive methylation and glucuronidation. The resulting methylcatechol glucuronide is the major circulating metabolite.
The mean oral clearance of tadalafil is 2.5 L/hr, and the terminal half-life is 17.5 hours in healthy subjects. After a single oral dose, Cmax is achiev within 30 minutes.
Long-term once daily dosing of tadalafil 5 mg is safe and well-tolerated in male patients. Despite the complexities of assessing the tolerability of this treatment, the analysis of six studies with adequate patient populations indicates that once-daily tadalafil is a viable treatment choice for men with ED. However, cost must be take into consideration. For many ED patients, this treatment option is not affordable and may be a financial burden.
Cost
Tadalafil medications for ED is particularly need for males because it has been found to be much more effective than Viagra, sildenafil and vardenafil. This is because it blocks a substance called phosphodiesterase-5 enzyme (PDE-5).
PDE-5 inhibitors increase blood flow to the penis, and this increases an erection. This makes it possible to have a sexual encounter when you want.
It also has a long half-life and so can work for up to 36 hours per dose. This means that it can be take as and when need, or on a daily basis to provide continuous treatment.
A person may be able to buy tadalafil through a mail-order pharmacy. This could help lower the cost of the drug. Some Medicare plans cover the costs of this type of service.
A patient can also talk with their doctor or pharmacist about online pharmacy options. Some of these services can also offer savings cards and other programs that can help pay for medications.
